Scientists learn how genes and environment conspire in pancreatic cancer development

Like weeds sprouting from cracks in the pavement, cancer often forms in sites of tissue damage. That damage could be an infection, a physical wound, or some type of inflammation. Common examples include stomach cancer caused by H. pylori infection, Barrett’s esophagus caused by acid reflux, and even smoking-induced lung cancer. Exactly how tissue damage […]

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Study reveals neurons responsible for rapidly stopping behaviors, actions

For the first time in humans, investigators at Cedars-Sinai have identified the neurons responsible for canceling planned behaviors or actions—a highly adaptive skill that when lost, can lead to unwanted movements. Known as “stop signal neurons,” these neurons are critical in powering someone to stop or abort an action they have already put in process. […]

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Study examines role of biomarkers to evaluate kidney injury in cancer patients

A study by Mayo Clinic researchers published in Kidney International Reports finds that immune checkpoint inhibitors, may have negative consequences in some patients, including acute kidney inflammation, known as interstitial nephritis. Immune checkpoint inhibitors are used to treat cancer by stimulating the immune system to attack cancerous cells. “Immune checkpoint inhibitors have improved the prognosis […]

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Experimental HIV vaccine primed immune system as first stage in production of broadly neutralizing antibodies

A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today. The vaccine showed success in stimulating production of rare immune cells needed to start the process of generating antibodies against the fast-mutating virus; the targeted response was detected in 97 percent of […]

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